Automatic pipetting – both efficient and ergonomic!

  • Fully automatic pipetting

  • Compact pipetting robot ASSIST PLUS from INTEGRA Biosciences

  • A strong and satisfied project team: Garry Müller, Andreas Städler and Stephanie Stursberg from INTEGRA Biosciences and David Semprevivo from Leuze electronic

  • Tip ejection box: monitoring of the tip ejection takes place here using the PRK 3B polarized retro-reflective photoelectric sensor from Leuze electronic

Automatic pipetting – both efficient and ergonomic!

The exact and efficient transfer of samples in extremely small dosing volumes is essential in the life sciences industry. For this purpose, INTEGRA Biosciences AG developed a compact pipetting robot called ASSIST PLUS that draws and pipettes samples into the target container. Part of this process is the automatic loading and ejecting of pipette tips, monitored by a customer-specific solution developed by Leuze electronic specially for INTEGRA Biosciences based on the polarized PRK 3B retro-reflective photoelectric sensor.

Electronic pipetting – today a must in every lab!

Modern laboratories, whether in the biotech or pharmaceutical industry or in the academic realm, process and analyze an increasing quantity of samples. Yet the sample volumes and the corresponding labware are becoming smaller. The high sample quantity and strict requirements on accuracy and precision make manual pipetting a great challenge for the users. Furthermore, long, manual pipetting protocols can impact the health of the users, as classical, manual pipetting involves collecting and dispensing liquid using thumb movements. This can lead to the development of repetitive strain injuries. With modern pipettes, special focus is therefore placed on ergonomics by reducing the weight of the devices and by performing the pipetting operation electronically. An advantage of ASSIST PLUS is that the users themselves no longer need to pipette. The pipette can be clicked into the ASSIST PLUS holder, and the protocol is performed automatically. To prevent cross contamination of samples during critical applications, pipette tips are used only once. ASSIST PLUS does this by automatically loading new tips and then ejecting them into the provided tip waste container after the pipetting operation.

Customer-specific solution for INTEGRA Biosciences

There are many providers of retro-reflective photoelectric sensors. But only one was able to satisfy all demands – and could do so for the price of a standard solution: David Semprevivo from Leuze electronic made it possible. Together with the Industry Manager for Labor Automation, Dr. Lutz Werner, who is based at the Leuze electronic headquarters in Owen/Teck, the Swiss key account manager sought out possibilities that could turn this application request into reality. The sensor-reflector solution that was found is based on the PRK 3B polarized retro-reflective photoelectric sensor from Leuze electronic. This is the world's smallest retro-reflective photoelectric sensor with laser and autocollimation principle. With its small housing dimensions of just 32 x 11 x 17 mm in the standard compact version, it could easily be integrated in the likewise compact pipetting robot from INTEGRA Biosciences. With special dimensions, deflected cable and special reflector, this solution became a complete product developed just for INTEGRA Biosciences. Especially for this, the subsidiary of Leuze electronic in Fluringen, Switzerland, set up a small warehouse so as to be able to flexibly respond to the quantities ordered by INTEGRA Biosciences at any time. "It is important to us to be able to individually meet our customers' requests at all times and to make use of our years of industry experience in the area of lab automation," says David Semprevivo. "A fast delivery time is also a must for us." INTEGRA Biosciences can thereby be supplied with the requested quantities within no more than two days.

Participating companies

INTEGRA Biosciences AG, Zizers (CH)
Founded in 1965, the company is headquartered in Zizers, Switzerland. There, nearly 100 employees develop devices for liquid handling and culture media production; 210 employees work for INTEGRA Biosciences worlwide. For the global sales of its lab devices and customer support, INTEGRA Biosciences has its own direct sales and support subsidiaries in the USA, Canada, China, Great Britain, France, Germany, Austria and Switzerland as well as a global network of sales partners.

Leuze electronic GmbH + Co. KG, Owen
More than 50 years experience have made Leuze electronic real experts in innovative and efficient sensor solutions for industrial automation. Its main focus is on the areas of intralogistics, packaging industry, machine tools and automotive industry as well as laboratory automation. The product range includes switching and measuring sensors, identification systems, solutions for image processing and data transmission and also occupational safety components and systems. Leuze electronic was founded in 1963 at the current headquarters of the sensor system manufacturer in Owen/Teck, southern Germany. With its extensive international sales and service network, competent consulting and reliable customer service, Leuze electronic serves customers worldwide. More than 1200 sensor people at 22 locations are involved in development, production, sales and service – supported by more than 40 sales partners around the world. Every single day, each one of them delivers the Smart Sensor Business promise to their customers: to think easy, share experience, offer proximity and create the future.


  • Branch/Area

    Laboratory Automation (sample processing)

  • Duty

    Control engineering

  • Application

    Automatic pipetting – both efficient and ergonomic!